Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.

Nitric oxide produced by cytokine-inducible nitric oxide synthase (iNOS) is thought to be important in the pathogenesis of septic shock. To further our understanding of the role of iNOS in normal biology and in a variety of inflammatory disorders, including septic shock, we have used gene targeting...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Laubach, V E, Shesely, E G, Smithies, O, Sherman, P A
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40677/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479866/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.23.10688
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