Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts

BACKGROUND: In vivo studies have demonstrated the ability of multi-walled carbon nanotubes (MWCNT) to induce airway remodeling, a key feature of chronic respiratory diseases like asthma and chronic obstructive pulmonary disease. However, the mechanism leading to remodeling is poorly understood. Part...

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Main Authors: Hussain, Salik, Sangtian, Stacey, Anderson, Shamika M, Snyder, Ryan J, Marshburn, Jamie D, Rice, Annette B, Bonner, James C, Garantziotis, Stavros
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067690/
https://ncbi.nlm.nih.gov/pubmed/24915862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-11-28
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