Irradiated Compared with Nonirradiated NSG Mice for the Development of a Human B-Cell Lymphoma Model

NOD.Cg-Prkdc(scid) Il2rg(tm1Wjl)/SzJ (NSG) mice are a superior strain for the engraftment of human tumors, as they provide an ideal model to explore the potency, toxicity, and dosage of therapeutic drugs. Although whole-body nonlethal irradiation is often performed to enhance engraftment, the need f...

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Bibliografiske detaljer
Main Authors: Chadalavada, Deepti, Adamson, Trinka W, Burnett, John C, Chen, Robert W, Rossi, John J
Format: Artigo
Sprog:Inglês
Udgivet: American Association for Laboratory Animal Science 2014
Fag:
Mouse Models
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067581/
https://ncbi.nlm.nih.gov/pubmed/24956209
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