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Effective Inhibition of c-MET-mediated Signaling, Growth, and Migration of Ovarian Cancer Cells is Influenced by the Ovarian Tissue Microenvironment

The signaling mediated by c-MET and its ligand, hepatocyte growth factor (HGF), has been implicated in malignant progression of cancer involving stimulation of proliferation, invasion, and metastasis. We studied the c-MET/HGF axis as a mediator of tumor-stromal interaction in ovarian cancer and the...

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Detalhes bibliográficos
Main Authors: Kwon, Youngjoo, Smith, Bryan D, Zhou, Yan, Kaufman, Michael D, Godwin, Andrew K
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067476/
https://ncbi.nlm.nih.gov/pubmed/24362531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.539
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