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S100A8/A9 mRNA Induction in an Ex Vivo Model of Endotoxin Tolerance: Roles of IL-10 and IFNγ

OBJECTIVES: Septic syndromes are the leading cause of death in intensive care units. They are characterized by the development of immune dysfunctions such as endotoxin tolerance (ET), whose intensity and duration are associated with increased risk of nosocomial infections and mortality. Alarmins S10...

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Bibliographische Detailangaben
Hauptverfasser: Fontaine, Mathieu, Planel, Séverine, Peronnet, Estelle, Turrel-Davin, Fanny, Piriou, Vincent, Pachot, Alexandre, Monneret, Guillaume, Lepape, Alain, Venet, Fabienne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067416/
https://ncbi.nlm.nih.gov/pubmed/24956170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100909
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