Modulation of Radiation Injury Response in Retinal Endothelial Cells by Quinic Acid Derivative KZ-41 Involves p38 MAPK

Radiation-induced damage to the retina triggers leukostasis, retinal endothelial cell (REC) death, and subsequent hypoxia. Resultant ischemia leads to visual loss and compensatory retinal neovascularization (RNV). Using human RECs, we demonstrated that radiation induced leukocyte adhesion through me...

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Detalhes bibliográficos
Main Authors: Toutounchian, Jordan J., Steinle, Jena J., Makena, Patrudu S., Waters, Christopher M., Wilson, Matthew W., Haik, Barrett G., Miller, Duane D., Yates, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067294/
https://ncbi.nlm.nih.gov/pubmed/24956278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100210
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