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Fully Deacetylated Chitooligosaccharides Act as Efficient Glycoside Hydrolase Family 18 Chitinase Inhibitors

Small molecule inhibitors against chitinases have potential applications as pesticides, fungicides, and antiasthmatics. Here, we report that a series of fully deacetylated chitooligosaccharides (GlcN)(2–7) can act as inhibitors against the insect chitinase OfChtI, the human chitinase HsCht, and the...

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書誌詳細
主要な著者: Chen, Lei, Zhou, Yong, Qu, Mingbo, Zhao, Yong, Yang, Qing
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067223/
https://ncbi.nlm.nih.gov/pubmed/24828498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.564534
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