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Fully Deacetylated Chitooligosaccharides Act as Efficient Glycoside Hydrolase Family 18 Chitinase Inhibitors

Small molecule inhibitors against chitinases have potential applications as pesticides, fungicides, and antiasthmatics. Here, we report that a series of fully deacetylated chitooligosaccharides (GlcN)(2–7) can act as inhibitors against the insect chitinase OfChtI, the human chitinase HsCht, and the...

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Detalhes bibliográficos
Main Authors: Chen, Lei, Zhou, Yong, Qu, Mingbo, Zhao, Yong, Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067223/
https://ncbi.nlm.nih.gov/pubmed/24828498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.564534
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