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The Stoichiometry and Biophysical Properties of the Kv4 Potassium Channel Complex with K(+) Channel-interacting Protein (KChIP) Subunits Are Variable, Depending on the Relative Expression Level

Kv4 is a voltage-gated K(+) channel, which underlies somatodendritic subthreshold A-type current (I(SA)) and cardiac transient outward K(+) (I(to)) current. Various ion channel properties of Kv4 are known to be modulated by its auxiliary subunits, such as K(+) channel-interacting protein (KChIP) or...

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Autores principales: Kitazawa, Masahiro, Kubo, Yoshihiro, Nakajo, Koichi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067195/
https://ncbi.nlm.nih.gov/pubmed/24811166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563452
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