Intestine-specific Deletion of Acyl-CoA:Monoacylglycerol Acyltransferase (MGAT) 2 Protects Mice from Diet-induced Obesity and Glucose Intolerance

The absorption of dietary fat involves the re-esterification of digested triacylglycerol in the enterocytes, a process catalyzed by acyl-CoA:monoacylglycerol acyltransferase (MGAT) 2. Mice without a functional gene encoding MGAT2 (Mogat2(−/−)) are protected from diet-induced obesity. Surprisingly, t...

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Bibliographic Details
Main Authors: Nelson, David W., Gao, Yu, Yen, Mei-I, Yen, Chi-Liang Eric
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067168/
https://ncbi.nlm.nih.gov/pubmed/24784138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555961
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