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Contributions of the σ(W), σ(M), and σ(X) Regulons to the Lantibiotic Resistome of Bacillus subtilis

In Bacillus subtilis, the extracytoplasmic function (ECF) σ factors σ(M), σ(W), and σ(X) all contribute to resistance against lantibiotics. Nisin, a model lantibiotic, has a dual mode of action: it inhibits cell wall synthesis by binding lipid II, and this complex also forms pores in the cytoplasmic...

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Detalhes bibliográficos
Main Authors: Kingston, Anthony W., Liao, Xiaojie, Helmann, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067139/
https://ncbi.nlm.nih.gov/pubmed/23980836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12380
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