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Contributions of the σ(W), σ(M), and σ(X) Regulons to the Lantibiotic Resistome of Bacillus subtilis
In Bacillus subtilis, the extracytoplasmic function (ECF) σ factors σ(M), σ(W), and σ(X) all contribute to resistance against lantibiotics. Nisin, a model lantibiotic, has a dual mode of action: it inhibits cell wall synthesis by binding lipid II, and this complex also forms pores in the cytoplasmic...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067139/ https://ncbi.nlm.nih.gov/pubmed/23980836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12380 |
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