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microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway

BACKGROUND: We aimed to investigate whether MIR31 is an oncogene in human endometrial cancer and identify the target molecules associated with the malignant phenotype. METHODS: We investigated the growth potentials of MIR31-overexpressing HEC-50B cells in vitro and in vivo. In order to identify the...

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Detalhes bibliográficos
Main Authors: Mitamura, Takashi, Watari, Hidemichi, Wang, Lei, Kanno, Hiromi, Kitagawa, Makiko, Hassan, Mohamed Kamel, Kimura, Taichi, Tanino, Mishie, Nishihara, Hiroshi, Tanaka, Shinya, Sakuragi, Noriaki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067122/
https://ncbi.nlm.nih.gov/pubmed/24779718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-97
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