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Systems biology and proteomic analysis of cerebral cavernous malformation

Cerebral cavernous malformations (CCM) are vascular anomalies caused by mutations in genes encoding KRIT1, OSM and PDCD10 proteins causing hemorrhagic stroke. We examine proteomic change of loss of CCM gene expression. Using human umbilical vein endothelial cells, label-free differential protein exp...

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Detalhes bibliográficos
Main Authors: Edelmann, Alexander R, Schwartz-Baxter, Sarah, Dibble, Christopher F, Byrd, Warren C, Carlson, Jim, Saldarriaga, Ivandario, Bencharit, Sompop
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066995/
https://ncbi.nlm.nih.gov/pubmed/24684205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14789450.2014.896742
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