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Exercise, APOE genotype, and the evolution of the human lifespan
Humans have exceptionally long lifespans compared with other mammals. However, our longevity evolved when our ancestors had two copies of the apolipoprotein E (APOE) ε4 allele, a genotype that leads to a high risk of Alzheimer’s disease (AD), cardiovascular disease, and increased mortality. How did...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066890/ https://ncbi.nlm.nih.gov/pubmed/24690272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2014.03.001 |
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