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Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury

Endothelial cells (ECs) are an essential component of the hematopoietic microenvironment, which maintains and regulates hematopoietic stem cells (HSCs). Although ECs can support the regeneration of otherwise lethally-irradiated HSCs, the mechanisms are not well understood. To further understand this...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zachman, Derek K., Leon, Ronald P., Das, Prerna, Goldman, Devorah C., Hamlin, Kimberly L., Guha, Chandan, Fleming, William H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066846/
https://ncbi.nlm.nih.gov/pubmed/23939266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2013.07.001
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