Ligand-dependent corepressor contributes to transcriptional repression by C(2)H(2) zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1

We identified a novel interaction between ligand-dependent corepressor (LCoR) and the corepressor KRAB-associated protein-1 (KAP-1). The two form a complex with C(2)H(2) zinc-finger transcription factor ZBRK1 on an intronic binding site in the growth arrest and DNA-damage-inducible α (GADD45A) gene...

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Bibliographische Detailangaben
Hauptverfasser: Calderon, Mario R., Verway, Mark, Benslama, Radia Ouelaa, Birlea, Mirela, Bouttier, Manuella, Dimitrov, Vassil, Mader, Sylvie, White, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066800/
https://ncbi.nlm.nih.gov/pubmed/24829459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku413
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