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De novo detection of differentially bound regions for ChIP-seq data using peaks and windows: controlling error rates correctly

A common aim in ChIP-seq experiments is to identify changes in protein binding patterns between conditions, i.e. differential binding. A number of peak- and window-based strategies have been developed to detect differential binding when the regions of interest are not known in advance. However, care...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lun, Aaron T.L., Smyth, Gordon K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066778/
https://ncbi.nlm.nih.gov/pubmed/24852250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku351
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