Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2

The antiglycemic drug metformin, widely prescribed as first-line treatment of type II diabetes mellitus, has lifespan-extending properties. Precisely how this is achieved remains unclear. Via a quantitative proteomics approach using the model organism Caenorhabditis elegans, we gained molecular unde...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: De Haes, Wouter, Frooninckx, Lotte, Van Assche, Roel, Smolders, Arne, Depuydt, Geert, Billen, Johan, Braeckman, Bart P., Schoofs, Liliane, Temmerman, Liesbet
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066537/
https://ncbi.nlm.nih.gov/pubmed/24889636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321776111
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi