Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILRα

Paired Ig-like type 2 receptor α (PILRα) recognizes a wide range of O-glycosylated mucin and related proteins to regulate broad immune responses. However, the molecular characteristics of these recognitions are largely unknown. Here we show that sialylated O-linked sugar T antigen (sTn) and its atta...

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Detalhes bibliográficos
Main Authors: Kuroki, Kimiko, Wang, Jing, Ose, Toyoyuki, Yamaguchi, Munechika, Tabata, Shigekazu, Maita, Nobuo, Nakamura, Seiko, Kajikawa, Mizuho, Kogure, Amane, Satoh, Takeshi, Arase, Hisashi, Maenaka, Katsumi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066494/
https://ncbi.nlm.nih.gov/pubmed/24889612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324105111
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