Engineering of a red-light–activated human cAMP/cGMP-specific phosphodiesterase

Sensory photoreceptors elicit vital physiological adaptations in response to incident light. As light-regulated actuators, photoreceptors underpin optogenetics, which denotes the noninvasive, reversible, and spatiotemporally precise perturbation by light of living cells and organisms. Of particular...

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Bibliographic Details
Main Authors: Gasser, Carlos, Taiber, Sandra, Yeh, Chen-Min, Wittig, Charlotte Helene, Hegemann, Peter, Ryu, Soojin, Wunder, Frank, Möglich, Andreas
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066486/
https://ncbi.nlm.nih.gov/pubmed/24889611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321600111
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