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Behçet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity

The HLA protein, HLA-B*51, encoded by HLA-B in MHC, is the strongest known genetic risk factor for Behçet disease (BD). Associations between BD and other factors within the MHC have been reported also, although strong regional linkage disequilibrium complicates their confident disentanglement from H...

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Autori principali: Ombrello, Michael J., Kirino, Yohei, de Bakker, Paul I. W., Gül, Ahmet, Kastner, Daniel L., Remmers, Elaine F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066484/
https://ncbi.nlm.nih.gov/pubmed/24821759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406575111
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