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Geldanamycin and Its Derivatives Inhibit the Growth of Myeloma Cells and Reduce the Expression of the MET Receptor

Introduction. Geldanamycin (GA) is an ansamycin antibiotic that exhibits potent anti-neoplastic properties. The aim of this study was to assess the impact of GA and its derivatives on the growth and invasiveness of myeloma cell lines and CD138+ cells derived from the bone marrow of patients with mul...

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Main Authors: Jurczyszyn, Artur, Zebzda, Anna, Czepiel, Jacek, Perucki, William, Bazan-Socha, Stanisława, Cibor, Dorota, Owczarek, Danuta, Majka, Marcin
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066360/
https://ncbi.nlm.nih.gov/pubmed/24959301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.8731
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