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Three-dimensional super-resolution and localization of dense clusters of single molecules

When a single molecule is detected in a wide-field microscope, the image approximates the point spread function of the system. However, as the distribution of molecules becomes denser and their images begin to overlap, existing solutions to determine the number of molecules present and their precise...

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Detalhes bibliográficos
Main Authors: Barsic, Anthony, Grover, Ginni, Piestun, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066253/
https://ncbi.nlm.nih.gov/pubmed/24953078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05388
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