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Three-dimensional super-resolution and localization of dense clusters of single molecules

When a single molecule is detected in a wide-field microscope, the image approximates the point spread function of the system. However, as the distribution of molecules becomes denser and their images begin to overlap, existing solutions to determine the number of molecules present and their precise...

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Библиографические подробности
Главные авторы: Barsic, Anthony, Grover, Ginni, Piestun, Rafael
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066253/
https://ncbi.nlm.nih.gov/pubmed/24953078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05388
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