STI571 (Glivec) suppresses the expression of vascular endothelial growth factor in the gastrointestinal stromal tumor cell line, GIST-T1

AIM: To estimate whether STI571 inhibits the expression of vascular endothelial growth factor (VEGF) in the gastrointestinal stromal tumor (GIST) cells. METHODS: We used GIST cell line, GIST-T1. It has a heterogenic 57-bp deletion in exon 11 to produce a mutated c-KIT, which results in constitutive...

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Detalhes bibliográficos
Main Authors: Jin, Toufeng, Nakatani, Hajime, Taguchi, Takahiro, Nakano, Takumi, Okabayashi, Takehiro, Sugimoto, Takeki, Kobayashi, Michiya, Araki, Keijiro
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066119/
https://ncbi.nlm.nih.gov/pubmed/16521182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i5.703
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