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Construction of retroviral vector of p(125FAK) specific ribozyme genes and its effects on BGC-823 cells

AIM: To construct the retroviral vector of p(125FAK) specific ribozyme genes and to explore the feasibility of ribozyme in BGC-823 gene therapy in vitro. METHODS: A hammerhead ribozyme DNA targeting p(125FAK) mRNA from nt 1010 to nt 1032 was synthesized and recombinated into the retroviral vector pL...

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Detalhes bibliográficos
Main Authors: Guan, Guo-Xian, Jian, Hong-Xing, Lei, Dong-Yin, Lu, Hui-Shan, Zhang, Xiang-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066116/
https://ncbi.nlm.nih.gov/pubmed/16521179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i5.686
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