A truncated hepatitis E virus ORF2 protein expressed in tobacco plastids is immunogenic in mice

AIM: To cost-effectively express the 23-ku pE2, the most promising subunit vaccine encoded by the E2 fragment comprising of the 3’-portion of hepatitis E virus (HEV) open reading frame 2 (ORF2) in plastids of tobacco (Nicotiana tabacum cv. SR1), to investigate the transgene expression and pE2 accumu...

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Detalhes bibliográficos
Main Authors: Zhou, Yuan-Xiang, Lee, Maggie Yuk-Ting, Ng, James Ming-Him, Chye, Mee-Len, Yip, Wing-Kin, Zee, Sze-Yong, Lam, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2006
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066044/
https://ncbi.nlm.nih.gov/pubmed/16482635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i2.306
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