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Interferon-α response in chronic hepatitis B-transfected HepG2.2.15 cells is partially restored by lamivudine treatment

AIM: To characterize the IFN-response and its modul-ation by the antiviral compound lamivudine in HBV-transfected HepG2.2.15 cells. METHODS: HepG2.2.15 and HepG2 cells were stimulated with various concentrations of IFN-α2a in the presence or absence of lamivudine. Then, total RNA was extracted and a...

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Autors principals: Guan, Shi-He, Lu, Mengji, Grünewald, Petra, Roggendorf, Michael, Gerken, Guido, Schlaak, Jörg F
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065950/
https://ncbi.nlm.nih.gov/pubmed/17226901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i2.228
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