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TNF-alpha polymorphisms as a potential modifier gene in the cystic fibrosis

Modifier genes, as the TNF-α gene, can modulate the cystic fibrosis (CF) severity. Thus, -238G>A and -308G>A polymorphisms of TNF-α gene were analyzed as modifiers of CF. In this context, the present study enrolled 49 CF patients (diagnosis performed by sweat test and complete CFTR screening)....

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Detalhes bibliográficos
Main Authors: Coutinho, Cyntia AAC, Marson, Fernando AL, Marcelino, Aline RB, Bonadia, Luciana C, Carlin, Marcelo P, Ribeiro, Antonio F, Ribeiro, Jose D, Bertuzzo, Carmen S
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065397/
https://ncbi.nlm.nih.gov/pubmed/24959313
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