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Development and Validation of a UPLC Method by the QbD-Approach for the Estimation of Rabeprazole and Levosulpiride from Capsules

Statistical experimental design was used to optimize the chromatographic separations of two pharmaceutical compounds from their respective potential impurities. A fractional factorial design was utilized to study the effects of pH, organic solvent in mobile phases A&B, and flow rate on the resol...

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Dettagli Bibliografici
Autori principali: Thummala, Veera Raghava Raju, Seshadri, Raja Kumar, Tharlapu, Satya Sankarsana Jagan Mohan, Ivaturi, Mrutyunjaya Rao, Nittala, Someswara Rao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Österreichische Apotheker-Verlagsgesellschaft 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065125/
https://ncbi.nlm.nih.gov/pubmed/24959404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1310-17
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