A carregar...

Metformin Impairs Mitochondrial Function in Skeletal Muscle of Both Lean and Diabetic Rats in a Dose-Dependent Manner

Metformin is a widely prescribed drug for the treatment of type 2 diabetes. Previous studies have demonstrated in vitro that metformin specifically inhibits Complex I of the mitochondrial respiratory chain. This seems contraindicative since muscle mitochondrial dysfunction has been linked to the pat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wessels, Bart, Ciapaite, Jolita, van den Broek, Nicole M. A., Nicolay, Klaas, Prompers, Jeanine J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065055/
https://ncbi.nlm.nih.gov/pubmed/24950069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100525
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!