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Ablation of Coactivator Med1 Switches the Cell Fate of Dental Epithelia to That Generating Hair
Cell fates are determined by specific transcriptional programs. Here we provide evidence that the transcriptional coactivator, Mediator 1 (Med1), is essential for the cell fate determination of ectodermal epithelia. Conditional deletion of Med1 in vivo converted dental epithelia into epidermal epith...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065011/ https://ncbi.nlm.nih.gov/pubmed/24949995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099991 |
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