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Genetic and comparative analyses reveal an alternative secondary structure in the region of nt 912 of Escherichia coli 16S rRNA.

Mutations at position 912 of Escherichia coli 16S rRNA result in two notable phenotypes. The C-->U transition confers resistance to streptomycin, a translational-error-inducing antibiotic, while a C-->G transversion causes marked retardation of cell growth rate. Starting with the slow-growing G912 m...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Lodmell, J S, Gutell, R R, Dahlberg, A E
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40650/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479839/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.23.10555
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