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Pathways for Small Molecule Delivery to the Central Nervous System Across the Blood-Brain Barrier
The treatment of central nervous system (CNS) disease has long been difficult due to the ineffectiveness of drug delivery across the blood-brain barrier (BBB). This review summarizes important concepts of the BBB in normal versus pathophysiology and how this physical, enzymatic, and efflux barrier p...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Libertas Academica
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4064947/ https://ncbi.nlm.nih.gov/pubmed/24963272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/PMC.S13384 |
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