Destabilization of Heterologous Proteins Mediated by the GSK3β Phosphorylation Domain of the β-Catenin Protein

BACKGROUND AND AIMS: Wnt/β-catenin signaling plays important roles in development and cellular processes. The hallmark of canonical Wnt signaling activation is the stabilization of β-catenin protein in cytoplasm and/or nucleus. The stability of β-catenin is the key to its biological functions and is...

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Detalhes bibliográficos
Main Authors: Kong, Yuhan, Zhang, Hongyu, Chen, Xian, Zhang, Wenwen, Zhao, Chen, Wang, Ning, Wu, Ningning, He, Yunfeng, Nan, Guoxin, Zhang, Hongmei, Wen, Sheng, Deng, Fang, Liao, Zhan, Wu, Di, Zhang, Junhui, Qin, Xinyue, Haydon, Rex C., Luu, Hue H., He, Tong-Chuan, Zhou, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064945/
https://ncbi.nlm.nih.gov/pubmed/24335169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354518
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