Development of an in vitro model to measure bioactivity of botulinum neurotoxin A in rat bladder muscle strips

BACKGROUND: Botulinum toxin A (BoNT-A) is a new treatment modality in various causes of bladder dysfunction; like neurogenic detrusor overactivity and overactive bladder. The best technique of administrating BoNT-A in patients is unknown. A validated in vitro model could be used to investigate newer...

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Hlavní autoři: van Uhm, Janneke IM, Beckers, Goedele MA, van der Laarse, Willem J, Meuleman, Eric JH, Geldof, Albert A, Nieuwenhuijzen, Jakko A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Technical Advance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064817/
https://ncbi.nlm.nih.gov/pubmed/24885301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2490-14-37
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