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Intrinsic Brain Activity of Cognitively Normal Older Persons Resembles More That of Patients Both with and at Risk for Alzheimer's Disease Than That of Healthy Younger Persons

In Alzheimer's disease (AD), recent findings suggest that amyloid-β (Aβ)-pathology might start 20–30 years before first cognitive symptoms arise. To account for age as most relevant risk factor for sporadic AD, it has been hypothesized that lifespan intrinsic (i.e., ongoing) activity of hetero-...

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Detalhes bibliográficos
Main Authors: Pasquini, Lorenzo, Tonch, Annika, Plant, Claudia, Zherdin, Andrew, Ortner, Marion, Kurz, Alexander, Förstl, Hans, Zimmer, Claus, Grimmer, Timo, Wohlschäger, Afra, Riedl, Valentin, Sorg, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064725/
https://ncbi.nlm.nih.gov/pubmed/24689864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/brain.2013.0213
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