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An optogenetic tool for the activation of endogenous diaphanous-related formins induces thickening of stress fibers without an increase in contractility
We have developed an optogenetic technique for the activation of diaphanous related formins. Our approach is based on fusion of the Light-Oxygen-Voltage 2 domain of Avena sativa Phototrophin1 to an isolated Diaphanous Autoregulatory Domain from mDia1. This “caged” diaphanous autoregulatory domain wa...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4064713/ https://ncbi.nlm.nih.gov/pubmed/23677607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21115 |
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