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Peripheral and site-specific CD4(+)CD28(null) T cells from Rheumatoid Arthritis patients show distinct characteristics

Proinflammatory CD4(+)CD28(null) T cells are frequently found in the circulation of RA patients, but are less common in the rheumatic joint. In the present study we sought to identify functional differences between CD4(+)CD28(null) T cells from blood and synovial fluid in comparison to conventional...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pieper, Jennifer, Johansson, Sara, Snir, Omri, Linton, Ludvig, Rieck, Mary, Buckner, Jane H, Winqvist, Ola, van Vollenhoven, Ronald, Malmström, Vivianne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064710/
https://ncbi.nlm.nih.gov/pubmed/24313359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/sji.12139
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