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Selection of pancreatic cancer cell-binding landscape phages and their use in development of anticancer nanomedicines

It is hypothesized that the use of targeted drug delivery systems can significantly improve the therapeutic index of small molecule chemotherapies by enhancing accumulation of the drugs at the site of disease. Phage display offers a high-throughput approach for selection of the targeting ligands. We...

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Autores principales: Bedi, Deepa, Gillespie, James W., Petrenko, Valery A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064708/
https://ncbi.nlm.nih.gov/pubmed/24899628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzu020
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