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Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury
Following brain injury, microglia assume a reactive-like state and secrete pro-inflammatory molecules that can potentiate damage. A therapeutic strategy that may limit microgliosis is of potential interest. In this context, selective estrogen receptor modulators, such as raloxifene and tamoxifen, ar...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4064706/ https://ncbi.nlm.nih.gov/pubmed/24999330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00132 |
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