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The Sigma-2 (σ(2)) Receptor: A Novel Protein for the Imaging and Treatment of Cancer

The sigma-2 (σ(2)) receptor is an important target for the development of molecular probes in oncology because of its 10-fold higher density in proliferating tumor cells than in quiescent tumor cells, and the observation that σ(2) receptor agonists are able to kill tumor cells via apoptotic and non-...

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Bibliographic Details
Main Authors: Mach, Robert H., Zeng, Chenbo, Hawkins, William G.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064612/
https://ncbi.nlm.nih.gov/pubmed/23734634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301545c
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