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The cleft lip and palate defects in Dancer mutant mice result from gain of function of the Tbx10 gene
Cleft lip and palate (CL/P) is a common disfiguring birth defect with complex, poorly understood etiology. Mice carrying a spontaneous mutation, Dancer (Dc), exhibit CL/P in homozygotes and show significantly increased susceptibility to CL/P in heterozygotes [Deol, M. S. & Lane, P. W. (1966) J....
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2004
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406459/ https://ncbi.nlm.nih.gov/pubmed/15118109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401025101 |
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