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Design of synthetic yeast promoters via tuning of nucleosome architecture
Model-based design of biological parts is a critical goal of synthetic biology, especially for eukaryotes. Here we demonstrate that nucleosome architecture can play a role in defining yeast promoter activity and utilize a computationally-guided approach that can enable both the redesign of endogenou...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4064463/ https://ncbi.nlm.nih.gov/pubmed/24862902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5002 |
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