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Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1–matrix metalloproteinase substrates

By proteolytic modification of low abundant signaling proteins and membrane receptors, proteases exert potent posttranslational control over cell behavior at the postsecretion level. Hence, substrate discovery is indispensable for understanding the biological role of proteases in vivo. Indeed, matri...

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Bibliographische Detailangaben
Hauptverfasser: Tam, Eric M., Morrison, Charlotte J., Wu, Yi I., Stack, M. Sharon, Overall, Christopher M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC406442/
https://ncbi.nlm.nih.gov/pubmed/15118097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305862101
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