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Does the antihyperalgesic disruptor of endothelial cells, octoxynol-9, alter nociceptor function?

The vasoactive mediator, endothelin-1, elicits a novel form of hyperalgesia, stimulation-dependent hyperalgesia. Acting on its cognate receptor on the vascular endothelial cell, endothelin-1 produces a state in which mechanical stimulation now elicits release of pronociceptive mediators from endothe...

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Main Authors: Chen, Xiaojie, Green, Paul G., Levine, Jon D.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064416/
https://ncbi.nlm.nih.gov/pubmed/24790171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00034.2014
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