Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

Haploidentical natural killer (NK) cell infusions can induce remissions in some patients with acute myeloid leukemia (AML) but regulatory T-cell (Treg) suppression may reduce efficacy. We treated 57 refractory AML patients with lymphodepleting cyclophosphamide and fludarabine followed by NK cell inf...

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Autors principals: Bachanova, Veronika, Cooley, Sarah, Defor, Todd E., Verneris, Michael R., Zhang, Bin, McKenna, David H., Curtsinger, Julie, Panoskaltsis-Mortari, Angela, Lewis, Dixie, Hippen, Keli, McGlave, Philip, Weisdorf, Daniel J., Blazar, Bruce R., Miller, Jeffrey S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Plenary Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064329/
https://ncbi.nlm.nih.gov/pubmed/24719405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-532531
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