Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP.
The second messenger cAMP stimulates the expression of numerous genes via the protein kinase A-mediated phosphorylation of the cAMP response element-binding protein (CREB) at Ser-133. Ser-133 phosphorylation, in turn, appears to induce target gene expression by promoting interaction between CREB and...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40643/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.23.10521 |
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