Human adipose derived stromal/stem cells (hASCs) protect against STZ-induced hyperglycemia; analysis of hASC-derived paracrine effectors

Adipose-derived stromal/stem cells (ASCs) ameliorate hyperglycemia in rodent models of islet transplantation and autoimmune diabetes, yet the precise human ASC (hASC)-derived factors responsible for these effects remain largely unexplored. Here, we show that systemic administration of hASCs improved...

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Hauptverfasser: Kono, Tatsuyoshi M., Sims, Emily K., Moss, Dan R., Yamamoto, Wataru, Ahn, Geonyoung, Diamond, Julie, Tong, Xin, Day, Kathleen H., Territo, Paul R., Hanenberg, Helmut, Traktuev, Dmitry O., March, Keith L., Evans-Molina, Carmella
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063872/
https://ncbi.nlm.nih.gov/pubmed/24519994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1676
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