Structure of CbpA J-Domain Bound to the Regulatory Protein CbpM Explains Its Specificity and Suggests Evolutionary Link between CbpM and Transcriptional Regulators

CbpA is one of the six E. coli DnaJ/Hsp40 homologues of DnaK co-chaperones and the only one that is additionally regulated by a small protein CbpM, conserved in γ-proteobacteria. CbpM inhibits the co-chaperone and DNA binding activities of CbpA. This regulatory function of CbpM is accomplished throu...

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Autores principales: Sarraf, Naghmeh S., Shi, Rong, McDonald, Laura, Baardsnes, Jason, Zhang, Linhua, Cygler, Miroslaw, Ekiel, Irena
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063869/
https://ncbi.nlm.nih.gov/pubmed/24945826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100441
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