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Broad scope method for creating humanized animal models for animal health and disease research through antibiotic treatment and human fecal transfer

Traditionally, mouse humanization studies have used human fecal transfer to germ-free animals. This practice requires gnotobiotic facilities and is restricted to gnotobiotic mouse lines, which limits humanized mouse research. We have developed a generalizable method to humanize non germ-free mice us...

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Detalhes bibliográficos
Main Authors: Hintze, Korry J, Cox, James E, Rompato, Giovanni, Benninghoff, Abby D, Ward, Robert E, Broadbent, Jeff, Lefevre, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063843/
https://ncbi.nlm.nih.gov/pubmed/24637796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.28403
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