Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer

Cancer is as much an epigenetic disease as a genetic one; however, the interplay between these two processes is unclear. Recently, it has been shown that a large proportion of DNA methylation variability can be explained by allele-specific methylation (ASM), either at classical imprinted loci or tho...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Romanelli, Valeria, Nakabayashi, Kazuhiko, Vizoso, Miguel, Moran, Sebastián, Iglesias-Platas, Isabel, Sugahara, Naoko, Simón, Carlos, Hata, Kenichiro, Esteller, Manel, Court, Franck, Monk, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063837/
https://ncbi.nlm.nih.gov/pubmed/24589629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28323
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky